diff --git a/src/msw/listctrl.cpp b/src/msw/listctrl.cpp
index edb0f4923c..292bb286ff 100644
--- a/src/msw/listctrl.cpp
+++ b/src/msw/listctrl.cpp
@@ -2140,11 +2140,12 @@ bool wxListCtrl::MSWOnNotify(int idCtrl, WXLPARAM lParam, WXLPARAM *result)
                                              wxLIST_STATE_SELECTED);
 
                     // <Enter> or <Space> activate the selected item if any (but
-                    // not with Shift and/or Ctrl as then they have a predefined
-                    // meaning for the list view)
+                    // not with modified keys pressed as they have a predefined
+                    // meaning for the list view then)
                     if ( lItem != -1 &&
                          (wVKey == VK_RETURN || wVKey == VK_SPACE) &&
-                         !(wxIsShiftDown() || wxIsCtrlDown()) )
+                         !(wxIsShiftDown() || wxIsCtrlDown() ||
+                             (GetKeyState(VK_MENU) < 0)) )
                     {
                         eventType = wxEVT_COMMAND_LIST_ITEM_ACTIVATED;
                     }