diff --git a/src/gtk/button.cpp b/src/gtk/button.cpp
index ca6fe2fc15..6121109932 100644
--- a/src/gtk/button.cpp
+++ b/src/gtk/button.cpp
@@ -119,7 +119,17 @@ bool wxButton::Create(wxWindow *parent,
     else if (HasFlag(wxBU_BOTTOM))
         y_alignment = 1.0;
 
+#ifdef __WXGTK4__
+    if (useLabel)
+    {
+        g_object_set(gtk_bin_get_child(GTK_BIN(m_widget)),
+            "xalign", x_alignment, "yalign", y_alignment, NULL);
+    }
+#else
+    wxGCC_WARNING_SUPPRESS(deprecated-declarations)
     gtk_button_set_alignment(GTK_BUTTON(m_widget), x_alignment, y_alignment);
+    wxGCC_WARNING_RESTORE()
+#endif
 
     if ( useLabel )
         SetLabel(label);
@@ -259,6 +269,13 @@ bool wxButton::DoSetLabelMarkup(const wxString& markup)
 GtkLabel *wxButton::GTKGetLabel() const
 {
     GtkWidget* child = gtk_bin_get_child(GTK_BIN(m_widget));
+#ifdef __WXGTK4__
+    if (GTK_IS_LABEL(child))
+        return GTK_LABEL(child);
+
+    return NULL;
+#else
+    wxGCC_WARNING_SUPPRESS(deprecated-declarations)
     if ( GTK_IS_ALIGNMENT(child) )
     {
         GtkWidget* box = gtk_bin_get_child(GTK_BIN(child));
@@ -274,6 +291,8 @@ GtkLabel *wxButton::GTKGetLabel() const
     }
 
     return GTK_LABEL(child);
+    wxGCC_WARNING_RESTORE()
+#endif
 }
 #endif // wxUSE_MARKUP
 
@@ -283,6 +302,8 @@ void wxButton::DoApplyWidgetStyle(GtkRcStyle *style)
     GtkWidget* child = gtk_bin_get_child(GTK_BIN(m_widget));
     GTKApplyStyle(child, style);
 
+#ifndef __WXGTK4__
+    wxGCC_WARNING_SUPPRESS(deprecated-declarations)
     // for buttons with images, the path to the label is (at least in 2.12)
     // GtkButton -> GtkAlignment -> GtkHBox -> GtkLabel
     if ( GTK_IS_ALIGNMENT(child) )
@@ -297,6 +318,8 @@ void wxButton::DoApplyWidgetStyle(GtkRcStyle *style)
             }
         }
     }
+    wxGCC_WARNING_RESTORE()
+#endif
 }
 
 wxSize wxButton::DoGetBestSize() const
diff --git a/src/gtk/checkbox.cpp b/src/gtk/checkbox.cpp
index 997f81fb55..72beb09210 100644
--- a/src/gtk/checkbox.cpp
+++ b/src/gtk/checkbox.cpp
@@ -123,7 +123,13 @@ bool wxCheckBox::Create(wxWindow *parent,
         m_widgetCheckbox = gtk_check_button_new();
 
         m_widgetLabel = gtk_label_new("");
+#ifdef __WXGTK4__
+        g_object_set(m_widgetLabel, "xalign", 0.0f, NULL);
+#else
+        wxGCC_WARNING_SUPPRESS(deprecated-declarations)
         gtk_misc_set_alignment(GTK_MISC(m_widgetLabel), 0.0, 0.5);
+        wxGCC_WARNING_RESTORE()
+#endif
 
         m_widget = gtk_box_new(GTK_ORIENTATION_HORIZONTAL, 0);
         gtk_box_pack_start(GTK_BOX(m_widget), m_widgetLabel, FALSE, FALSE, 3);
diff --git a/src/gtk/filectrl.cpp b/src/gtk/filectrl.cpp
index 0ab9103b48..a50a83b27d 100644
--- a/src/gtk/filectrl.cpp
+++ b/src/gtk/filectrl.cpp
@@ -339,11 +339,9 @@ bool wxGtkFileCtrl::Create( wxWindow *parent,
     if ( style & wxFC_SAVE )
         gtkAction = GTK_FILE_CHOOSER_ACTION_SAVE;
 
-    m_widget =  gtk_alignment_new ( 0, 0, 1, 1 );
-    g_object_ref(m_widget);
     m_fcWidget = GTK_FILE_CHOOSER( gtk_file_chooser_widget_new(gtkAction) );
-    gtk_widget_show ( GTK_WIDGET( m_fcWidget ) );
-    gtk_container_add ( GTK_CONTAINER ( m_widget ), GTK_WIDGET( m_fcWidget ) );
+    m_widget = GTK_WIDGET(m_fcWidget);
+    g_object_ref(m_widget);
 
     m_focusWidget = GTK_WIDGET( m_fcWidget );
 
diff --git a/src/gtk/mdi.cpp b/src/gtk/mdi.cpp
index 4437030362..dd86d5c83e 100644
--- a/src/gtk/mdi.cpp
+++ b/src/gtk/mdi.cpp
@@ -422,7 +422,13 @@ void wxMDIClientWindow::AddChildGTK(wxWindowGTK* child)
         s = _("MDI child");
 
     GtkWidget *label_widget = gtk_label_new( s.mbc_str() );
+#ifdef __WXGTK4__
+    g_object_set(label_widget, "xalign", 0.0f, NULL);
+#else
+    wxGCC_WARNING_SUPPRESS(deprecated-declarations)
     gtk_misc_set_alignment( GTK_MISC(label_widget), 0.0, 0.5 );
+    wxGCC_WARNING_RESTORE()
+#endif
 
     GtkNotebook* notebook = GTK_NOTEBOOK(m_widget);
 
diff --git a/src/gtk/stattext.cpp b/src/gtk/stattext.cpp
index b84ddd9073..9c1031f9fb 100644
--- a/src/gtk/stattext.cpp
+++ b/src/gtk/stattext.cpp
@@ -108,7 +108,13 @@ bool wxStaticText::Create(wxWindow *parent,
 
     // GTK_JUSTIFY_LEFT is 0, RIGHT 1 and CENTER 2
     static const float labelAlignments[] = { 0.0, 1.0, 0.5 };
+#ifdef __WXGTK4__
+    g_object_set(m_widget, "xalign", labelAlignments[justify], NULL);
+#else
+    wxGCC_WARNING_SUPPRESS(deprecated-declarations)
     gtk_misc_set_alignment(GTK_MISC(m_widget), labelAlignments[justify], 0.0);
+    wxGCC_WARNING_RESTORE()
+#endif
 
     gtk_label_set_line_wrap( GTK_LABEL(m_widget), TRUE );