diff --git a/src/mac/carbon/app.cpp b/src/mac/carbon/app.cpp
index 1472ca610c..adb56a068c 100644
--- a/src/mac/carbon/app.cpp
+++ b/src/mac/carbon/app.cpp
@@ -717,7 +717,9 @@ bool wxApp::OnInitGui()
 
 void wxApp::CleanUp()
 {
+#if wxUSE_TOOLTIPS
     wxToolTip::RemoveToolTips() ;
+#endif
 
     // One last chance for pending objects to be cleaned up
     wxTheApp->DeletePendingObjects();