diff --git a/src/gtk/listbox.cpp b/src/gtk/listbox.cpp
index ef4042412b..edacaa6463 100644
--- a/src/gtk/listbox.cpp
+++ b/src/gtk/listbox.cpp
@@ -646,7 +646,7 @@ void wxListBox::GTKOnSelectionChanged()
     else // single selection
     {
         const int item = GetSelection();
-        if ( DoChangeSingleSelection(item) )
+        if (item >= 0 && DoChangeSingleSelection(item))
             SendEvent(wxEVT_LISTBOX, item, true);
     }
 }