diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 3893f048c6..d91d7334b6 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -20,13 +20,53 @@ jobs:
     runs-on: ${{ matrix.runner }}
     name: ${{ matrix.name }}
     strategy:
+      fail-fast: false
       matrix:
         include:
+          - name: wxGTK 2 Ubuntu 16.04
+            runner: ubuntu-16.04
+            gtk_version: 2
+          - name: wxGTK 3 Ubuntu 16.04 static
+            runner: ubuntu-16.04
+            configure_flags: --disable-shared
+          - name: wxGTK 2 UTF-8 Ubuntu 18.04
+            runner: ubuntu-18.04
+            gtk_version: 2
+            configure_flags: --enable-utf8 --enable-utf8only --enable-monolithic
+          - name: wxGTK 3 STL Ubuntu 18.04
+            runner: ubuntu-18.04
+            configure_flags: --enable-cxx11 --enable-stl --disable-compat30
+          - name: wxGTK 3 Ubuntu 18.04 with clang
+            runner: ubuntu-18.04
+            compiler: clang
+            configure_flags: --disable-sys-libs --with-libcurl
+          - name: wxGTK ANSI Ubuntu 20.04
+            runner: ubuntu-20.04
+            configure_flags: --disable-unicode
+            skip_samples: true
           - name: wxGTK Ubuntu 20.04 with ASAN
             runner: ubuntu-20.04
             configure_flags: --disable-compat30 --disable-sys-libs --with-libcurl
             skip_samples: true
             use_asan: true
+          - name: wxX11 Ubuntu 18.04
+            runner: ubuntu-18.04
+            configure_flags: --with-x11 --enable-pch --disable-stc
+            skip_samples: true
+          - name: wxDFB Ubuntu 18.04
+            runner: ubuntu-18.04
+            configure_flags: --with-directfb --enable-pch --disable-stc
+            skip_samples: true
+            allow_warnings: true
+          - name: wxMotif Ubuntu 18.04
+            runner: ubuntu-18.04
+            configure_flags: --with-motif --enable-pch --disable-stc
+            skip_samples: true
+          - name: wxQt Ubuntu 18.04
+            runner: ubuntu-18.04
+            configure_flags: --with-qt --enable-pch --without-opengl
+            skip_samples: true
+
     env:
       wxGTK_VERSION: ${{ matrix.gtk_version && matrix.gtk_version || 3 }}
       wxCONFIGURE_FLAGS: ${{ matrix.configure_flags }}