diff --git a/include/wx/private/spinctrl.h b/include/wx/private/spinctrl.h
index af2ae47270..e0a59db1cc 100644
--- a/include/wx/private/spinctrl.h
+++ b/include/wx/private/spinctrl.h
@@ -26,6 +26,8 @@ extern int GetMaxValueLength(int minVal, int maxVal, int base);
 // of wxSpinCtrl is derived from wxSpinButton but uses the same algorithm.
 extern wxSize GetBestSize(const wxControl* spin, int minVal, int maxVal, int base);
 
+// Helper function to check if given combination of range and base is valid.
+extern bool IsBaseCompatibleWithRange(int minVal, int maxVal, int base);
 } // namespace wxSpinCtrlImpl
 
 #endif // _WX_PRIVATE_SPINCTRL_H_
diff --git a/interface/wx/spinctrl.h b/interface/wx/spinctrl.h
index 3bef883df2..edb2ac83b6 100644
--- a/interface/wx/spinctrl.h
+++ b/interface/wx/spinctrl.h
@@ -149,11 +149,15 @@ public:
         the numbers in the specified base when they are changed using the spin
         control arrows.
 
+        @note Under wxMSW setting a base to 16 is allowed only if current range
+        does not include negative values.
+
         @param base
             Numeric base, currently only 10 and 16 are supported.
         @return
             @true if the base was successfully changed or @false if it failed,
-            usually meaning that either the base is not 10 or 16.
+            usually meaning that either the base is not 10 or 16 or that
+            the base is not supported for values in the current range.
 
         @since 2.9.5
      */
@@ -166,6 +170,9 @@ public:
         it's not inside the new valid range, e.g. it will become @a minVal if
         it is less than it now. However no @c wxEVT_SPINCTRL
         event is generated, even if it the value does change.
+
+        @note Under wxMSW setting a range including negative values is silently
+        ignored if current base is set to 16.
     */
     void SetRange(int minVal, int maxVal);
 
diff --git a/src/common/spinctrlcmn.cpp b/src/common/spinctrlcmn.cpp
index 42e571dfac..2d5bba4b43 100644
--- a/src/common/spinctrlcmn.cpp
+++ b/src/common/spinctrlcmn.cpp
@@ -137,4 +137,10 @@ wxSize wxSpinCtrlImpl::GetBestSize(const wxControl* spin,
     return spin->GetSizeFromText(largestString);
 }
 
+bool wxSpinCtrlImpl::IsBaseCompatibleWithRange(int minVal, int maxVal, int base)
+{
+    // Negative values in the range are allowed only if base == 10
+    return base == 10 || (minVal >= 0 && maxVal >= 0);
+}
+
 #endif // wxUSE_SPINCTRL
diff --git a/src/msw/spinctrl.cpp b/src/msw/spinctrl.cpp
index 01cc251835..b297f3922e 100644
--- a/src/msw/spinctrl.cpp
+++ b/src/msw/spinctrl.cpp
@@ -421,6 +421,10 @@ int wxSpinCtrl::GetBase() const
 
 bool wxSpinCtrl::SetBase(int base)
 {
+    // For negative values in the range only base == 10 is allowed
+    if ( !wxSpinCtrlImpl::IsBaseCompatibleWithRange(m_min, m_max, base) )
+        return false;
+
     if ( !::SendMessage(GetHwnd(), UDM_SETBASE, base, 0) )
         return false;
 
@@ -537,6 +541,12 @@ WXHWND wxSpinCtrl::MSWGetFocusHWND() const
 
 void wxSpinCtrl::SetRange(int minVal, int maxVal)
 {
+    // Negative values in the range are allowed only if base == 10
+    if ( !wxSpinCtrlImpl::IsBaseCompatibleWithRange(minVal, maxVal, GetBase()) )
+    {
+        return;
+    }
+
     // Manually adjust the old value to avoid an event being sent from
     // NormalizeValue() called from inside the base class SetRange() as we're
     // not supposed to generate any events from here.