diff --git a/include/wx/chkconf.h b/include/wx/chkconf.h
index 437ccd8ac4..a8749d7371 100644
--- a/include/wx/chkconf.h
+++ b/include/wx/chkconf.h
@@ -319,6 +319,14 @@
 #   endif
 #endif /* !defined(wxUSE_ACCEL) */
 
+#ifndef wxUSE_ACCESSIBILITY
+#   ifdef wxABORT_ON_CONFIG_ERROR
+#       error "wxUSE_ACCESSIBILITY must be defined."
+#   else
+#       define wxUSE_ACCESSIBILITY 0
+#   endif
+#endif /* !defined(wxUSE_ACCESSIBILITY) */
+
 #ifndef wxUSE_ANIMATIONCTRL
 #   ifdef wxABORT_ON_CONFIG_ERROR
 #       error "wxUSE_ANIMATIONCTRL must be defined."
@@ -1232,6 +1240,15 @@
  */
 #if wxUSE_GUI
 
+#if wxUSE_ACCESSIBILITY && !defined(__WXMSW__)
+#   ifdef wxABORT_ON_CONFIG_ERROR
+#       error "wxUSE_ACCESSIBILITY is currently only supported under wxMSW"
+#   else
+#       undef wxUSE_ACCESSIBILITY
+#       define wxUSE_ACCESSIBILITY 0
+#   endif
+#endif /* wxUSE_ACCESSIBILITY */
+
 #if wxUSE_BUTTON || \
     wxUSE_CALENDARCTRL || \
     wxUSE_CARET || \