diff --git a/setup.h.in b/setup.h.in
index 58d5fe8531..94fa168605 100644
--- a/setup.h.in
+++ b/setup.h.in
@@ -460,6 +460,7 @@
 
 #define wxUSE_HELP        0
 
+#define wxUSE_MS_HTML_HELP 0
 
 #define wxUSE_WXHTML_HELP 0