diff --git a/setup.h.in b/setup.h.in
index 0e596334db..966aad994d 100644
--- a/setup.h.in
+++ b/setup.h.in
@@ -545,7 +545,7 @@
 #define wxUSE_DRAG_AND_DROP 0
 
 #ifdef __WXMSW__
-#define wxUSE_ACCESSIBILITY 1
+#define wxUSE_ACCESSIBILITY 0
 #else
 #define wxUSE_ACCESSIBILITY 0
 #endif