diff --git a/setup.h.in b/setup.h.in
index 7d5121a0a5..97926023d8 100644
--- a/setup.h.in
+++ b/setup.h.in
@@ -739,11 +739,6 @@
  */
 #define wxUSE_OPENGL 0
 
-/*
- * Set to 1 to compile MS Windows XP theme engine support
- */
-#define wxUSE_UXTHEME 0
-
 /*
  * Work around a bug in GNU libc 5.x wcstombs() implementation.
  *
@@ -764,12 +759,6 @@
  * Use wxGetResource & wxWriteResource (change .Xdefaults)
  */
 #define wxUSE_X_RESOURCES 0
-/*
- * Use OLE and OLE Automation (MSW only)
- */
-#define wxUSE_OLE 0
-#define wxUSE_OLE_AUTOMATION 0
-#define wxUSE_ACTIVEX 0
 
 /*
  * Use MS HTML Help via libmspack (Unix)