diff --git a/docs/changes.txt b/docs/changes.txt
index 4c3af62f96..b9ddbc9b5b 100644
--- a/docs/changes.txt
+++ b/docs/changes.txt
@@ -577,6 +577,7 @@ GTK:
 - Implement native tab art for wxAUI (Jens Lody and Teodor Petrov).
 - Fix pasting large amounts of text (Bradley Hawkins).
 - Show gstreamer errors if wxMediaCtrl fails to play file.
+- Fix wxGridCellEnumEditor mouse handling (Fulvio Senore).
 
 MSW:
 
diff --git a/src/generic/grideditors.cpp b/src/generic/grideditors.cpp
index de8831342a..fabd2b9227 100644
--- a/src/generic/grideditors.cpp
+++ b/src/generic/grideditors.cpp
@@ -1596,6 +1596,14 @@ void wxGridCellEnumEditor::BeginEdit(int row, int col, wxGrid* grid)
     wxASSERT_MSG(m_control,
                  wxT("The wxGridCellEnumEditor must be Created first!"));
 
+    wxGridCellEditorEvtHandler* evtHandler = NULL;
+    if (m_control)
+        evtHandler = wxDynamicCast(m_control->GetEventHandler(), wxGridCellEditorEvtHandler);
+
+    // Don't immediately end if we get a kill focus event within BeginEdit
+    if (evtHandler)
+        evtHandler->SetInSetFocus(true);
+
     wxGridTableBase *table = grid->GetTable();
 
     if ( table->CanGetValueAs(row, col, wxGRID_VALUE_NUMBER) )
@@ -1618,6 +1626,22 @@ void wxGridCellEnumEditor::BeginEdit(int row, int col, wxGrid* grid)
     Combo()->SetSelection(m_index);
     Combo()->SetFocus();
 
+#ifdef __WXOSX_COCOA__
+    // This is a work around for the combobox being simply dismissed when a
+    // choice is made in it under OS X. The bug is almost certainly due to a
+    // problem in focus events generation logic but it's not obvious to fix and
+    // for now this at least allows to use wxGrid.
+    Combo()->Popup();
+#endif
+
+    if (evtHandler)
+    {
+        // When dropping down the menu, a kill focus event
+        // happens after this point, so we can't reset the flag yet.
+#if !defined(__WXGTK20__)
+        evtHandler->SetInSetFocus(false);
+#endif
+    }
 }
 
 bool wxGridCellEnumEditor::EndEdit(int WXUNUSED(row),