diff --git a/include/wx/platform.h b/include/wx/platform.h
index 731bcc6187..1b6b013d9b 100644
--- a/include/wx/platform.h
+++ b/include/wx/platform.h
@@ -541,7 +541,7 @@
 #endif
 
 #if defined (__WXMAC__)
-#    if !defined(WORDS_BIGENDIAN) && ( !defined(__MACH__) || ( defined(__BIG_ENDIAN__) && __BIG_ENDIAN__ ) )
+#    if ( !defined(__MACH__) || ( defined(__BIG_ENDIAN__) && __BIG_ENDIAN__ ) )
 #        define WORDS_BIGENDIAN 1
 #    endif
 #endif