diff --git a/setup.h_vms b/setup.h_vms
index ef7ea38e4a..ffadeb77ae 100644
--- a/setup.h_vms
+++ b/setup.h_vms
@@ -422,7 +422,11 @@ typedef pid_t GPid;
 
 #define wxUSE_STC 1
 
+#ifdef VMS_GTK2
 #define wxUSE_ACTIVITYINDICATOR 1
+#else
+#define wxUSE_ACTIVITYINDICATOR 0
+#endif
 #define wxUSE_ANIMATIONCTRL 1
 #define wxUSE_BANNERWINDOW  1
 #define wxUSE_BUTTON       1