diff --git a/.travis.yml b/.travis.yml
index 909d62a2c4..c15a2a4e58 100644
--- a/.travis.yml
+++ b/.travis.yml
@@ -38,6 +38,10 @@ jobs:
           compiler: gcc
           env: wxCONFIGURE_FLAGS="--disable-compat30 --disable-optimise --disable-unicode" wxSKIP_SAMPLES=1
           name: wxGTK ANSI Ubuntu 20.04
+        - dist: focal
+          compiler: gcc
+          env: wxCONFIGURE_FLAGS="--disable-compat30 --disable-sys-libs" wxSKIP_SAMPLES=1 wxUSE_ASAN=1
+          name: wxGTK Ubuntu 20.04 with ASAN
         - os: osx
           osx_image: xcode7.3
           compiler: clang
diff --git a/build/tools/before_install.sh b/build/tools/before_install.sh
index 8ad9fc453d..c385a64d7e 100755
--- a/build/tools/before_install.sh
+++ b/build/tools/before_install.sh
@@ -42,6 +42,24 @@ case $(uname -s) in
             done
 
             $SUDO apt-get install -y $libtoolkit_dev $pkg_install
+
+            if [ "$wxUSE_ASAN" = 1 ]; then
+                codename=$(lsb_release --codename --short)
+                # Enable the `-dbgsym` repositories.
+                echo "deb http://ddebs.ubuntu.com ${codename} main restricted universe multiverse
+                deb http://ddebs.ubuntu.com ${codename}-updates main restricted universe multiverse
+                deb http://ddebs.ubuntu.com ${codename}-proposed main restricted universe multiverse" | \
+                $SUDO tee --append /etc/apt/sources.list.d/ddebs.list
+
+                # Import the debug symbol archive signing key from the Ubuntu server.
+                # Note that this command works only on Ubuntu 18.04 LTS and newer.
+                $SUDO apt-get install -y ubuntu-dbgsym-keyring
+
+                $SUDO apt-get update
+
+                # Install the symbols to allow LSAN suppression list to work.
+                $SUDO apt-get install -y libfontconfig1-dbgsym
+            fi
         fi
         ;;
 
diff --git a/build/tools/travis-ci.sh b/build/tools/travis-ci.sh
index 04861afcc8..ac03343254 100755
--- a/build/tools/travis-ci.sh
+++ b/build/tools/travis-ci.sh
@@ -21,6 +21,11 @@ case $wxTOOLSET in
         fi
         cmake --version
 
+        if [ "$wxUSE_ASAN" = 1 ]; then
+            echo "ASAN currently isn't supported in CMake builds"
+            exit 1
+        fi
+
         echo 'travis_fold:start:configure'
         echo 'Configuring...'
         mkdir build_cmake
@@ -61,7 +66,20 @@ case $wxTOOLSET in
     *)
         echo 'travis_fold:start:configure'
         echo 'Configuring...'
-        ./configure --disable-optimise --disable-debug_info $wxCONFIGURE_FLAGS || rc=$?
+
+        wxCONFIGURE_OPTIONS="--disable-optimise $wxCONFIGURE_FLAGS"
+        if [ "$wxUSE_ASAN" = 1 ]; then
+            export LSAN_OPTIONS=suppressions=$(pwd)/misc/suppressions/lsan
+
+            wxASAN_CFLAGS="-fsanitize=address -fno-omit-frame-pointer"
+            wxASAN_CXXFLAGS=$wxASAN_CFLAGS
+            wxASAN_LDFLAGS="-fsanitize=address"
+
+            ./configure $wxCONFIGURE_OPTIONS --enable-debug "CFLAGS=$wxASAN_CFLAGS" "CXXFLAGS=$wxASAN_CXXFLAGS" "LDFLAGS=$wxASAN_LDFLAGS" || rc=$?
+        else
+            ./configure $wxCONFIGURE_OPTIONS --disable-debug_info || rc=$?
+        fi
+
         if [ -n "$rc" ]; then
             echo '*** Configuring failed, contents of config.log follows: ***'
             echo '-----------------------------------------------------------'