diff --git a/wxPython/src/gtk/misc2.cpp b/wxPython/src/gtk/misc2.cpp
index 6e5a51c59e..051cb332bf 100644
--- a/wxPython/src/gtk/misc2.cpp
+++ b/wxPython/src/gtk/misc2.cpp
@@ -145,7 +145,11 @@ IMP_PYCALLBACK_BOOL_STRINGSTRING(wxPyFontEnumerator, wxFontEnumerator, OnFontEnc
 
 
     bool wxThread_IsMain() {
+#ifdef WXP_WITH_THREAD
         return wxThread::IsMain();
+#else
+        return TRUE;
+#endif
     }
 
 class wxPyTipProvider : public wxTipProvider {
diff --git a/wxPython/src/misc2.i b/wxPython/src/misc2.i
index 9b49096983..9da8e9f530 100644
--- a/wxPython/src/misc2.i
+++ b/wxPython/src/misc2.i
@@ -410,7 +410,11 @@ public:
 
 %inline %{
     bool wxThread_IsMain() {
+#ifdef WXP_WITH_THREAD
         return wxThread::IsMain();
+#else
+        return TRUE;
+#endif
     }
 %}
 
diff --git a/wxPython/src/msw/misc2.cpp b/wxPython/src/msw/misc2.cpp
index f949974082..0d19b32cbe 100644
--- a/wxPython/src/msw/misc2.cpp
+++ b/wxPython/src/msw/misc2.cpp
@@ -145,7 +145,11 @@ IMP_PYCALLBACK_BOOL_STRINGSTRING(wxPyFontEnumerator, wxFontEnumerator, OnFontEnc
 
 
     bool wxThread_IsMain() {
+#ifdef WXP_WITH_THREAD
         return wxThread::IsMain();
+#else
+        return TRUE;
+#endif
     }
 
 class wxPyTipProvider : public wxTipProvider {